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Electricity demand continued to outpace supply, resulting in frequent and widespread shortages that were often exacerbated by the overall fragility of Pakistan's power infrastructure.
"There may be a reluctance to challenge the banks because of the overall fragility of the financial system," Mr. Christensen speculated.
As we develop strategies to prepare for an influenza pandemic, we need to address the overall fragility of the entire vaccine research and manufacturing enterprise (27, 36, 37 ).
Grip strength can provide a general indicator of overall fragility [ 1], while walking speed tests lower extremity function and time to rise from a chair assesses lower body strength [ 2].
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If the designer is aware of this constraint, he or she can ensure that overall fragilities are rare.
From this study, overall seismic fragility relations have been derived from extensive fragility analyses in terms of broad range of hazard levels for multiple performance levels which were achieved by new direct performance-based design using MR dampers.
This dual-task test was able to detect overall cognitive fragility possibly linked to normal cognitive aging or to a predementia state with a sensitivity of 71% and a specificity of 96%, and detected a change in executive function with a sensitivity of 89% and a specificity of 94%.
These data were compared with those recorded in the national hospitalizations database (SDO) to assess the overall incidence of fragility fractures occurring at hip and other sites, including also those events not resulting in hospital admissions.
The annual incidence of the overall most common fragility fractures (hip, wrist, vertebral, humeral, and ankle fractures) per 100 inhabitants has been estimated up to 1.53 in men aged older than 65 years and up to 3.94 in women of the same age group.
Specific topics need attention when it comes to preparing for the recovery; sleep, pain and fatigue issues, bodily changes and needs, the psychological impact of the procedure and overall feeling of fragility, the pattern and time frame of recovery, and preparing the relatives for the temporary changes in the family.
Our experience emphasizes the need to stratify subjects by SMA type, age and current gross motor abilities in future trials since the majority of outcome measures examined in this study were optimal for only a subset of subjects which was highly dependent on the subject's age, motor disability and the overall degree of medical fragility.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com