All activation steps in the complement cascade converge on the complement factor C3. Thus, C3 not only seems to be a good indicator for overall complement activation, but may also be of pathophysiological relevance at the fetal-maternal interface.
Although most clinical laboratories measure overall complement activity (CH50) as well as the levels of major complement proteins such as C3 and C4, these are not terribly helpful in most situations in which complement activation occurs because these complement proteins are acute phase reactants.
In addition, comparison of data derived from MRM analyses of exponential versus stationary phases, resulted in data that clustered more towards to the middle of the overall data set, indicating little change in the overall protein complement of core catabolic proteins examined, as the cells transitioned from exponential to stationary phase.
Thus, the overall isoform complement of mitochondrial enzymes is not majorly altered, but certain subspecies of distinct cardiac protein isoforms are changed due to the deficiency in dystrophin.
During both incidents 22 animal health officers were drafted in to supervise the rendering process giving an overall plant workforce complement of 157.
Overall, the tRNA complement of Eukaryotes is highly dynamic part of the genomes whose organization evolves rapidly and in a highly lineage specific manner - a behavior that is in striking contrast to the extreme conservation of sequence and function of the tRNAs themselves.
Bounty was a small vessel, 91 feet in overall length, with a complement of 46 men crammed into limited accommodation.
Each commanding officer modified his vessel's armaments to his liking, taking into consideration factors such as the overall tonnage of cargo, complement of personnel aboard, and planned routes to be sailed.
Each commanding officer modified his vessel's armaments to his liking while taking into consideration factors such as the overall tonnage of cargo, complement of personnel aboard, and planned routes to be sailed.
