Overall, PABC is biologically aggressive with the majority of these tumours being oestrogen and progesterone receptor negative and Her2-neu receptor positive.
The overall emphasis was on biologically and epidemiologically significant (>0.30 log10) differences in VL [19], [33].
In addition to providing an overall geometric description, various biologically motivated tests about the forms of epistasis are embedded in this framework.
It is assumed that the AO occurs only after a biologically meaningful overall threshold has been passed (Boekelheide and Andersen 2010; Ramirez et al. 2013).
This consideration suggests the potential for the "background" exposures of other toxicants to bring the dose-response for an individual chemical (which is biologically nonlinear overall) into the linear range for a human population, as noted by US EPA (2005) and NRC (2008).
Here we found that, overall, NJ provided more biologically sound results than UPGMA: the first two groups in the NJ-tree comprised brain tissues and endocrine glands; muscle and fat tissues have a predominantly structural function in the body, while the rest of tissues (liver, stomach, ileum and blood) have an important metabolic role.
The correlation we report between clinical progression-free survival and overexpression of p53, and its relationship to other clinical factors of importance in astrocytoma tumour progression, suggests that quantitative increases in expression of overall p53 protein are biologically significant in the neoplastic process of astrocytic tumours.
Overall, our results suggest that biologically prepared AgNPs not only exhibit potent bactericidal activity, but also inhibit the activity of biofilms.
It possesses only eight amino acids (Trp-Ser-His-Pro-Gln-Phe-Glu-Lys) with no particular overall charge and is therefore biologically inert.
The overall results indicated that the biologically synthesized AgNPs have antiproliferative activity through induction of apoptosis in MDA-MB-231 breast cancer cell line, suggesting that biologically synthesized AgNPs might be a potential alternative agent for human breast cancer therapy.
