Your English writing platform
Discover LudwigSuggestions(5)
Exact(21)
This leads to an extra delay for every transmission in layer i, which makes the overall aggregation delay of SA scheme high.
However, we show that the presence of the remainder of the sequence dramatically reduces the net overall aggregation propensity by negative design principles that we suggest are very common in biological systems as a result of evolutionary processes.
Fluorescence emission aggregation studies indicate that 1b is ca. 61% (DMSO) and 32% (phosphate buffer) less aggregated than the peripherally substituted ZnPc 1a suggesting that non-peripheral substitution decreased overall aggregation of the photosensitizers.
However, overall aggregation seems to be limited by genome length, perhaps regardless of the number of chromosomes comprising a genome.
Apart from the charge, another property that strongly influences the overall aggregation propensity of a protein sequence is its hydrophobicity [2], [25], [45].
The presence of these characteristic polar regions reduces the protein hydropathy and overall aggregation propensity but also limits the number and area associated to aggregation-prone sequence stretches.
Similar(39)
The overall CGI aggregation procedure is fairly complex, but the aggregation of the LME index is straightforward and is based on an arithmetic mean.
Moreover, because of their high concentrations, their low deposition propensity would contribute significantly to decrease the overall cytosol aggregation tendency and prevent the initiation of spontaneous, non-specific aggregation processes that can deplete the cell of less represented and/or functionally important proteins.
Therefore, it is conceivable that evolution would select for an overall decreased aggregation propensity in operons performing essential cellular functions.
The overall familial aggregation was assessed by calculating the OR through the exponential function exp.
An overall familial aggregation is also indicated by the results of the generalised estimating equations' approach.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com