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The PKs of PNU-159548 and PNU-169884 were linear over the dose range studied.
A reproducible output linearity was found over the dose range 0.03 4.5 mGy of great clinical relevance.
The dosimeter material develops an easily visible colour change, which is quantitative, highly reproducible and stable over the dose range of approximately 5 45 kGy.
In acute and chronic (long-term) studies, YOH has been found to be relatively free of side effects over the dose range predicted to be effective in ED.
However, average irradiation-hardening rates over the dose range of 0 dpa−DC (the dose to plastic instability at yield) are considerably lower for stainless steels due to their high uniform ductility.
Regression analysis of milk fat data suggested that MFD was not maximized over the dose levels investigated, despite delivery of 34.5 g of trans-10, cis-12 CLA in the 100-g dose of CLA.
Plasma levels are proportionate to the dose given; over the dose range of 0.5 to 3.0 mg, peak levels of 8.0 to 37 ng/mL were observed.
Over the dose range studied, average concentration – time curves (Figure 2A) and systemic exposure (Cmax and AUC0 48h, Figure 2B) increased proportionally to rapamycin dose (Figure 2 and Table 4).
36 Topotecan CLss was similar over the dose range administered.
Telapristone exhibited linear kinetics over the dose ranges tested.
The pharmacokinetics were linear over the dose range studied.
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