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Degradation of the extracellular matrix may be concomitant with BBB disruption and tissue softening, setting the stage for the most pronounced forms of brain swelling and leading to the development of severe cerebral edema over subsequent hours and days in stroke patients (reviewed in [12]).
Although the reasons for the observed overshoot are unclear, it may reflect the rapid release of both ANP and BNP from storage in atrial granules, resulting in some depletion of stored peptide, followed by a new steady state of production/release in response to changed haemodynamic stimuli over subsequent hours.
As pain experience over subsequent hours may be affected by the time of day of recruitment (those included later in the day will be scoring their pain during night hours when they may spend a greater proportion of time asleep), randomisation is stratified by morning/afternoon admission, as well as by recruitment centre.
As pain experienced over subsequent hours may be affected by the time of day of recruitment (participants included later in the day would score their pain during night hours when they may spend a greater proportion of time asleep), randomisation was stratified by the time of the first recorded pain score (morning or afternoon/evening), as well as by recruitment centre.
As pain experience over subsequent hours may be affected by the time of day of recruitment (those starting the trial later in the day would be scoring their pain during night hours when they may spend a greater proportion of time asleep), randomisation was stratified by time of the first recorded pain score (morning or afternoon/evening), as well as by recruitment centre.
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Previous studies in this area provide limited evidence of the short term utility of PCA in emergency patients but have not considered the management of pain over the subsequent hours after hospital admission.
Previous studies in this area have provided limited evidence of the short term utility of PCA in emergency patients but have not considered the management of pain over the subsequent hours after hospital admission.
These three recent studies provide further limited evidence of the short-term utility of PCA in emergency patients, but do not address the management of pain over the subsequent hours following hospital admission.
Therefore, we believe that the glucoregulatory effects of exercise observed over the subsequent hours or day(s) after each exercise bout (2– 4) are of greater relevance than the blood glucose concentrations measured immediately after exercise.
Activity-induced changes, including RNA and protein synthesis, are initiated during a salient experience, and perturbing these changes over subsequent minutes, hours, and days influences the stability and robustness of the memory of that experience22.
Up at 7am, the subsequent hours will be spent obsessing over documents that he hopes will overturn his conviction for one of Britain's most notorious multiple murders.
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