General Koster, asked by the Peers commission if he recalled seeing the village "pretty much up in smoke at that time when you flew over," responded simply, "No, sir, I don't".
"Be right over," responds my neighbor.
More generally, in an uncertain environment with imprecise cues, asymmetries in the costs and benefits of under-responding versus over-responding should help explain the use of general versus specific cues.
Scientists have suggested that this is akin to the way that, after heavy doses of anti-retroviral therapy, the strengthened immune system in a human AIDS patient may over-respond to a pre-existing infection and damage healthy tissue.
Under-responding can result in death, while continually over-responding can waste precious energy reserves and compromise important life history attributes such as growth and reproduction.
Mixed model repeated measures ANOVA indicated that participants who over-responded to the ovarian stimulation session (E2 > 10,500 pmol/l) showed significant enhanced pain responses under this condition (p = 0.004).
This means their sense level might over-respond or under-respond in one or multiple senses.
The flip side also applies – animals can over-respond to novel organisms that are not actually particularly dangerous.
However, whereas DRN-rats tend to over-respond to ambiguous cues (i.e. greater conditioned suppression), 5-HTTOE mice showed a decreased response (i.e. reduced freezing).
To determine if Skn7p causes a defect in mat formation downstream of Sln1p, hyperactive (D427E) or inactive (D427N) point mutants of SKN7 that either over-respond or under-respond to the Sln1p branch of the HOG pathway, respectively, were transformed into skn7 Δ.
180BR is a radiosensitive fibroblast cell line derived from a leukaemia patient who over-responded to RT and subsequently died of radiation morbidity.
