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An innovative use of the fractal measure of complexity, indexing the linearity of movement paths over replicate temporal scales, was applied to satellite tracking data collected from narwhals (Monodon monoceros) (n=20) in West Greenland and the eastern Canadian high Arctic.
In doing this, significant patterns were integrated over replicate clones and overrepresentation of different genes by multiple clones was corrected.
The resultant log2 ratios were analyzed by UCSF Sproc to yield the mean and standard deviation of the log2 ratios over replicate spots.
To estimate expresssion levels, read-counts for each gene were normalized by total exon length, averaged over replicate samples, and finally scaled to the 0 to 1 range using the same sigmoid function.
DNS analyses revealed that PcoPine and PcoAspen were able to release comparable amounts of reducing sugars from pine and aspen, with PcoPine slightly but consistently more efficient over replicate experiments (Fig. 6).
In each dataset, we averaged measurements over replicate samples, and then, for each probe, we divided expression values in treated samples by the values in the corresponding control samples (time 0 hr).
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The performance of the proposed HDLA model is then evaluated in comparison with Over Replicated Softmax Model (ORS M.
We took as the detection p-value the maximum for each probe set over replicates as a conservative estimate of detection.
One mutation causes over-replication, giving rise to a clone, which further over-replicates due to a second mutation, etc.
Plasmids that systematically over-replicate relative to their cell mates have a higher chance of fixing in a cell (intra-host selection).
For example, GmnnΔ/Δ white blood cells over-replicate their DNA when stimulated with growth factors [22], and GmnnΔ/Δ T lymphocytes show cell cycle defects when stimulated to proliferate in vitro [33].
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