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A single course consisted of consecutive administration for 28 days followed by a 2-week rest; administration was repeated over four courses.
The median (range) relative dose intensity (actual daily dose intensity divided by planned, full dose, dose intensity over four courses of treatment) was 0.97 (0.58–1.02) for cisplatin, 1.03 (0.58–0.95) for ifosfamide and 0.95 (0.63–1.03) for paclitaxel.
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Data-gathering from the whole cohort, cross-sectionally over four course settings, contribute to the strength of the study, providing a broad base for validation of scale results.
"We serve Long Island duckling as a specialty prepared with two recipes served over two courses.
His 1995 book British Food might offer a glimpse of the kind of food that awaits diners at Say Cheese – and over five courses too.
Over five courses and the best part of three hours, chef Nevio Sirotic presents me with the region's best offerings: his ever-changing menu is based on what's in season and is almost entirely locally sourced.
In 16 references, basic survey data, like course questionnaires or examples from students' pre- and post-tests, are often compared over two courses or between two courses (based on simple dichotomies of traditional versus flipped approaches).
Finally, we employ the data regarding the trial of using macrophage colony stimulating factor (M-CSF) over three courses of intensive chemotherapies to reduce febrile neutropenia incidence for acute myeloid leukemia patients to illustrate the use of these estimators.
Again, if over-prescription was perpetuated over five courses, this would be a waste of £87.70 and projecting over a typical year involving 162 patients, a saving of £14207.40 could be made.
Rituximab has been reported to be well-tolerated in a study of 2,578 patients with 5,013 patient-years of exposure [ 18]; over five courses of treatment, serious adverse events did not increase over time.
The patients were generally adults (mean age 26.2 years) with moderately to severely impaired lung function (mean FEV155.1%% predicted), who had averaged over five courses of inhaled tobramycin in the year before the study.
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