Imputation tends to over-assign the major genotype to the imputed SNPs, resulting in different allele frequency and therefore inflating the P value.
In different words, make sure you don't over-assign a specified resource to three-fold tasks, so that it's unlikely that that the resource will last to finish everything specified to it.
A long-simmering dispute over assigning credit for the artificial heart boiled over again during a conference last December at the University of Utah.
Meanwhile the agreement also allows the university to retain flexibility over assigning faculty positions on the basis of greatest need, as defined by student enrollment.
When an aide expressed concern over assigning such a hazardous mission to a unit without combat experience, General MacArthur recalled how the 5th Cavalry had fought alongside his father's troops in the campaign against Geronimo.
In fact, disagreement over assigning functions to cortical areas does exist, with some arguing that function may be tied to elements of experiment design [ 64].
There was some uncertainty over assigning malaria, sepsis or anaemia as a cause of death without the availability of test results.
Unlike commonly used "top BLAST hits" approach where a sequence is often "forced" to have an assignment, this approach allowed us to classify sequences down to the species level without over assigning more distantly related sequences to known species.
