But the endgame in Aleppo does change the parameters of the conflict, leaving the rebels with no hold over any strategically significant area of the country and no real bargaining chip to try to force the government into a negotiated settlement.
By the end of 2012, the law of cooperatives was approved, indicating a move away from government control over significant areas of agricultural production, services, small industries and transportation.
In Figure 4, images CX and CY illustrate the magnitude of the fouling, with many particles showing completely clogged pore entrances over a significant percentage of particle surface area.
In a report that prompted an angry response from the UK Border Agency UKBAA), Sir Al Aynsley-Green highlighted concerns over "significant areas" of healthcare for the 1,000 children held in the Yarl's Wood centre every year.
Altogether, 8T-SRAM can be designed without significant area penalty over 6T-SRAM.
"We see this as a significant growth area moving forward".
The shift in focus and mission within the Forest Service in recent years has occurred at the same time as concerns have grown over the ecological health of significant areas of the national forests (Sampson and Adams 1993; USDA/Forest Service 1993; GAO 1999).
The likelihood ratio test shows that model 5 has significant improvement over model 4, suggesting a significant relationship between area income level and individual health.
Independent studies show that, on a 12-year follow-up study of 11,000 people, vegetarians have a lower rate of mortality in some significant areas than non-vegetarians". Over 25 years ago, Dr. Dean Ornish reported that significant coronary heart disease could be reversed by omitting animal products and oils from the diet, a program approved by Medicare for payment in 2010.
Given the state's size, not all counties would be affected in quite the same way over the next few decades, but significant areas already are experiencing extreme heat, drought and wildfires.
