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This SERS immunoassay gives exact results over a broad linear range, reflecting clinically relevant HBsAg concentrations.
These HPV 16 and HPV 18 quantitative PCR assays with GAPDH normalization are reproducibly quantitative over a broad linear dynamic range allowing for application in epidemiologic studies for measurement of viral load.
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The cyclic voltammetric and amperometric results showed that PtAu supported on silica nanorods has superior performance over the corresponding monometallic counterparts, with a broad linear range from 5.0 μM to 72000 μM for H2O2, a detection limit of 2.6 μM, a sensitivity of 46.7 μA mM−1 cm−2 at a lower working potential of −0.20 V vs SCE, and has good stability and reproducibility.
The limit of detection (LOD, S/ N = 3) for 14,15-DiHETrE 14,15-DiHETrEETrE wand0.14nmol L−15 -EpETrEon column) and method provided for both analytes a broad linear detection range over three orders of magnitude (R ≥ 0.999) from the limit of quantification (LOQ, S/ N = 9) up to 800 nmol L−1.
The proposed immunosensor showed a broader linear range, good reproducibility, and storage stability.
Dilutions of 1 800 and 1 1600 gave relatively higher OD values with a broader linear range.
As examples, real-time RCA-based sensing platforms were designed and successfully used for quantitation of microRNA over broad linear ranges (8 orders of magnitude) with a detection limit of 4 aM (or 0.12 zmol).
It should be noted that while the dose-response curve for DNA adducts is generally linear, it does not follow that dose-response curves for gene mutations or chromosomal mutations are linear over a broad dose range (Swenberg et al., 2008).
In CSTR experiments the co-culture showed over a broad concentration range an almost linear correlation in consumption and production rates to the supply with complex nutrients.
The predicted frequency-dependence holds over a limited range of frequencies up to 25 Hz, whilst the relation between net peak current and a predicted hyperbolic tangent function of the amplitude is found to be linear over a broad range of amplitudes up to 100 mV.
Hence, the mechanical properties of the material appear remarkably linear over a broad range of stresses and strains.
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