Exact(2)
As shown in Figure 5E, KYSE180 cells had 285 062 CpGs that were methylated over a basal β-value of 0.6, whereas KYSE180_HOTAIR cells showed a 1.4% increase in CpG methylation.
Briefly, 2 × 10 Huh-7/HBSP/B[alpha]P or Huh-7/GFP/B[alpha]P were suspended in 0.3% agarose in DMEM supplemented with 10% FBS, and plated in 60 mm dishes over a basal layer of 0.6% agarose in the same medium.
Similar(58)
The ETC and mitochondria turn over at a basal rate, and more rapidly in response to signals such as starvation, and a reduced rate of replacement is expected to result in longer-lived structures that will be more susceptible to time-dependent damage and malfunction.
This finding led the authors to suggest that c-Met signalling directs progenitor cells towards a basal phenotype over luminal differentiation [ 27], which is reflected in the pattern of c-Met staining seen in different breast cancer subtypes (as discussed later).
During the cellular response to genotoxic stress PARP-1 rapidly associates with DNA damage, which robustly stimulates poly(ADP-ribose) production over a low basal level of PARP-1 activity.
Overall, these data and those of the literature show an over-representation of basal and ERBB2 cases in IBCs as compared with non-IBCs [ 30, 31].
In contrast, CLE209 was only induced about 5-fold over a much lower basal expression level relative to CLE210 such that CLE210 mRNA was ~37-fold more abundant than CLE209 at day 2 but only ~6-fold more abundant at day 10.
Both RARβ1 and RARβ2/5 are over-expressed in Basal relative to Luminal cells.
After the addition of ATP, the CBF showed a rapid increase followed by a plateau over the basal rate.
In no instance did LG produce a change over basal for either pERK or pGSK.
LPS injection induced an increase in ROS generation by PMNLs of 200 ± 42% over the basal with a peak at 1 h and another peak at 4 6 h.
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