Sentence examples for ovarian cluster from inspiring English sources
Furthermore, the majority of the ovarian cluster is conserved with human, with the exception of mir-322, nearest to the male cluster, whereas, the male cluster is almost entirely rodent-specific miRNAs.
This region of the BRCA2 has been designated the ovarian cluster region.
More specifically, the ovarian cluster is divided into two subclusters: an endometrioid-enriched cluster and a serous-enriched cluster.
Both these mutations were localized outside the Ovarian Cluster Cancer Region and were previously reported also by others in the BIC database (three times for the 9106C>T mutation and four times for the IVS16-2A>G mutatinn in all).
No substantial effect of increased risk of ovarian cancer was seen in the respective ovarian cluster regions of each gene and only a borderline significant reduction of breast cancer risk was seen for BRCA2.
The ovarian cluster segregates into two subclusters, one enriched for the endometrioids also containing the primary endometrium tumors and a cluster enriched with the serous tumors also enriched with the ovarian metastases.
Cluster 5 primarily has genes associated with ovarian cancer, cluster 6 has a large proportion of genes associated with breast and lung cancers, and cluster 7 has a large proportion of genes associated with breast and central nervous system cancers.
Breast, lung, cervix, endometrium, stomach and ovarian metastases cluster significantly in their respective primary tissue clusters while gastrointestinal metastases such as colon, rectum and rectosigmoid cluster with their tissue of destination.
Assessing the combined impact of mutation position, regarding the ovarian cancer cluster region (OCCR), and type of cancer family history (FH) on age-related penetrance of ovarian cancer (OC) in women from BRCA1/2 families from the northern Netherlands.
The 4081insA mutation is in the BRCA2 gene ovarian cancer cluster region (OCCR) in exon 11.
For BRCA2, it has been proposed that mutations within the central region of the gene, termed the ovarian cancer cluster region ('OCCR'), are particularly associated with ovarian cancers.
