Sentence examples for outward positioned from inspiring English sources
Two configurations studied are center located adiabatic section and outward positioned adiabatic section.
Thus, this Arginine was proposed to flip between these conformations during GTP hydrolysis: it might facilitate GTPase dimer formation in the outward position and act as an Arg-finger in the inward position.
This amino acid is part of an interhelical hydrogen-bonding network in the "non-rhodopsin" structures, and is involved in keeping TM6 in its outward position in the structures of opsin.
The results with the tetranucleotides are in complete agreement with those in Figure 1 in terms of peripheral inward localization of AnTm, the central inward localization of YTAR and YCAG/CTGR, the uniform inward localization of WTAW, the uniform outward localization of RACY/RGTY, and the central outward positioning of RCAY/RTGY, RCGY and RGCY.
Rotation of Tyr119 to the outward position results in an increased distance between the aromatic rings of these residues, resulting in a loss of this stabilization.
Glu247 (on TM6) is freed in Meta IIb from Arg135 and can form a salt bridge to Lys231 on TM5, thus stabilizing TM6 in the outward position.
In inactive kinases it is often possible for αC to assume an outward position, displaced away from the ATP binding site.
The dimeric transporter is captured in the crystal in an asymmetric state such that one domain occupies an outward position and the other is inward.
Y2195.58 forms a hydrogen bond with Y3267.53 of the highly conserved NPxxY motif in the crystal structures of the active state, holding helix 6 in the outward position.
After S4 immobilization in the outward position, mutant channels produce an inward omega current that most likely depolarizes the resting potential and produces the hypokalaemia-induced weakness.
The P2Y12R– 34 antagonist complex structure (PDB ID 4NTJ) revealed a wide open binding pocket due to the unresolved ECL1 and ECL2 regions and the outward positions of helices VI (TM6) and VII (TM7).
