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Due to their outstanding specificities, monoclonal antibodies (mAbs) have become one of the most popular products of the biopharmaceutical industry.
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Also a nonparametric hypothesis test, based on Bootstrap resampling, is used to determine whether the presence of the EMD block actually improves the performance.Results: The results show an outstanding specificity when the EMD block is used, even in very noisy conditions (0.96 compared to 0.72 for SNR = 8 dB), being always superior than that of the conventional SM alone.
From a statistical perspective, the automated model had excellent discrimination, was well-calibrated, and had outstanding specificity (94.3%) and good sensitivity (51.6%).
One limitation was the use of surrogate criteria when the formal criteria were not measured: our validation study showed that EHR metabolic syndrome (using both formal and surrogate criteria) had outstanding specificity (91%) for directly-assessed metabolic syndrome.
These unique properties, together with the outstanding specificity of A-T and G-C Watson Crick hydrogen-bonding interactions, make DNA a particularly promising candidate to serve as a building block material for a wide variety of nanostructures with potential applications in biomedicine and biotechnology.
The silver NA-SERS platform described here was previously shown to exhibit outstanding sensitivity and specificity for detection and differentiation of closely related strains of respiratory syncytial virus and rotavirus, even in biochemically complex backgrounds [10], [11].
Natural products have also made important contributions to cell biology due to their outstanding potency and specificity.
A ≥14% reduction of serum CEA level from baseline after 2 cycles of treatment in advanced NSCLC is an accurate measurement of OR compared to RECIST, it has outstanding sensitivity and specificity, and correlates well with PFS especially in adenocarcinoma histology.
In conclusion, GeneMarkS provided outstanding sensitivities but poor specificities for most sequence lengths longer than 100 nt.
In this article, we review the current investigative progress in the development of engineered whole-cell biocatalysts with excellent OP-hydrolyzing activity, a broad spectrum of substrate specificity, and outstanding stability for the detoxification and detection of OPs.
The measured performance of ELISA was so outstanding, with the sensitivity, specificity, positive predictive value, and negative predictive value levels exceeding 98%, that ELISA was chosen as a confirmation alternative.
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