In 2009 Elias and Schmuth postulated their new "outside-inside-outside" hypothesis referring to the pathogenesis of human AD (Elias and Schmuth 2009).
9 Briefly, breakdown of the skin barrier is recognized to be important in the development of AE; however, it is debated whether this event is secondary to the inflammatory response to irritants and allergens ("inside-outside hypothesis") or whether the barrier damage itself drives disease activity ("outside-inside hypothesis").
P values corrected for the number of comparisons made outside the hypothesis are presented as P corrected (Pc).
Let (N_{0}) be the Lebesgue-null set outside which hypotheses (J1), (J2), and (J4) hold.
Recent emerging evidence proposes a new paradigm regarding the sites/direction of the atherosclerotic process, the "outside-in" hypothesis.
The long-held view [ 1] that oral teeth first evolved by the co-option of dermal denticles at the oral margin when jaws evolved (the outside-in hypothesis) has been challenged by reconsideration of these fossil data.
One popular argument for the simulation hypothesis, outside of acid trips, came from Oxford University's Nick Bostrom in 2003 (although the idea dates back as far as the 17th-century philosopher René Descartes).
However, we found that the key was to test the hypothesis outside of the office.
13 In addition, several alternative pathways outside the melatonin hypothesis should be considered including behavioural or lifestyle changes and sleep disturbances 27 as these changes may also help explain increases in breast cancer risk among shift workers.
Furthermore, such widespread rotamer transitions represent changes between energetically separate states, thus placing doubt over the validity of the minimal rotation hypothesis outside the context of docking simulations and the small dataset upon which it was developed (Zavodszky and Kuhn, 2005).
In some cases, a stroke can affect brain function in ways outside of study hypotheses.
