Eldredge, the leader in the short program, fell on an attempted quadruple jump at the outset, watered down three other jumps and finished fourth.
Thus, drug solubility characteristics need to be established at the outset, including maximum water solubility or drug solubility in other common delivery solvents, such as dimethyl sulfoxide (DMSO) or methanol, before undertaking these types of screens.
It may cost a little more at the outset, but the water savings will be huge in the long run.
From the outset, Fernald knew that water might limit her ambitions at Belcampo.
At the outset, lignite, petroleum coke, distilled water, and additives were calculated and weighed in predetermined ratios.
The tree will be thirstiest its first day indoors, so continually check its water supply at the outset.
From the outset, chlorination has been the drinking water disinfectant of choice in the country.
From the outset, residents raised concerns that the new water source was causing a spate of rashes and hair loss.
At the outset of the response, workers distributed drinking water, clothing and other supplies to affected people and made evacuation centres a stress-free environment for children.
Indeed, water, it is said at the outset, has an "extraordinary capacity…to catalyse essential chemical reactions", making it the Earth's "most potent agent of change".
