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Hall made plans for two expansion packs from the outset of development, owing to the huge story.
This study of the effects of ocean warming and CO2 driven acidification on development and calcification of marine invertebrate larvae reared in experimental conditions from the outset of development (fertilization) shows the positive and negative effects of these stressors.
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It is also conceivable that defects in acquiring proper mitochondrial mass at the outset of neural development may play a role in development of neurodegenerative diseases later in life.
Facing a widespread revolt against property taxes, many of the same municipalities began financing suburban infrastructure — roads, sewers and so on — through "impact fees" levied at the outset of the development process.
This confirms the hypothesis of an Age × IQ interaction on the degree of differentiation of abilities and suggests that persons with low IQ do not exhibit a less differentiated pattern of intellectual abilities from the outset of their development.
Workforce and staffing were considered to be important from the outset of the development of the checklist.
Despite the challenges to evidence-based policy making, the fact remains that governments need to know at the outset of policy development, and after policies have been implemented, the likely and achieved impacts in terms of both the positive and negative outcomes.
An alternative approach is suggested, which takes its outset in arenas of development and increased awareness of actors and their way of interpreting context and performing interventions.
It follows from the presented results that a default strategy at the outset of a tracer development campaign for a new target is to identify molecules with a combination of high affinity for the target and low non-specific binding, i.e. minimal values for the Kd × Vu,brain product.
Another important approach that allows the ultimate robustness of chromatographic methods to be rigorously included as an objective from the outset of systematic method development was described in [ 7, 8].
One important aspect to notice is that, for this workflow to operate successfully, an adequate Quality Target Product Profile (QTPP) needs to be defined right at the outset of the drug development process (See ICH Q8(R2) for a definition of QTPP).
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