Exact(3)
In principle, the disappearance of identifiable cholinergic neurons might reflect either outright cell death or severe atrophy with downregulation of cholinergic markers.
With respect to tumor growth characteristics, moderate hypoxia causes a slowing of tumor cell proliferation, while severe hypoxia causes outright cell death [27], [28].
In combination therapy, BCL-2 inhibition, even when it does not cause outright cell death, can prime cancer cells so that they move closer to the threshold of commitment to apoptosis.
Similar(56)
The therapies that rely on restricting or encouraging movement are based on the idea that after a brain injury, a number of brain cells are killed outright, but many cells surrounding the injury are merely stunned.
Maintaining the outright ban on cell phone use is an overreaction to hypotheticals, and prevents positive uses of phones on flights.
Although attitudes are changing, when it comes to an outright ban on cell phone use while driving, most Americans aren't quite there yet.
The embryos lacking functional BRCA2 genes probably stopped growing because molecular "checkpoints" in the developing embryo either halt the division of cells with damaged DNA, so that the damage can be repaired, or kill the cells outright.
And standard chemotherapy with drugs meant to kill tumor cells outright is ineffective against kidney cancer, in part because the kidneys are designed to remove harmful substances from the body without being affected by them.
Because federal law allows municipalities to control general placement, construction and modification of cellphone towers but does not allow them to ban towers outright, local disputes over cell towers can drag on for years.
Thus, an outright elimination of all cells producing "incorrect answer" to any of many training examples would eventually lead to elimination of all cells.
Targeting of a single tumour antigen may allow for regression of the tumour by gene deletion or downregulation or by outright failure to target cells in the tumour not expressing the targeted antigen [ 97, 105].
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