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From D0 to D2, we daily collected the following parameters: non-renal SOFA score, patient's weight, 24-h urine output, dose of furosemide, fluid balance (intake output), mean arterial pressure, dose of vasopressors, use of mechanical ventilation, creatinine and urea blood and urine levels.
Subtracting 100 W output was judged as the optimal output dose without complications.
The fact is that the position of the isotope would affect the accuracy of the output dose.
In order to check the validity of the audit procedures and the relative parameters, we used the ion chamber and followed AAPM TG-21 to measure the daily output dose.
Deviation in dose distribution may exist in the delivery of a precisely designed intensity-modulated radiation therapy (IMRT) plan with several causes, including the mechanical inaccuracy of the therapeutic equipment, errors in the output dose characteristics, setup deviation, and anatomical changes of patients during the treatment process.
However, because this dose evaluation approach relies on the calculation results of TPS and does not consider the errors in the accelerator machinery and output dose accuracy, the validation of irradiation dose for the treatment should be performed through the combination of the proposed method and other online measurement methods.
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The simulated input-output dose response curves indicated the operation and design of the signaling structure necessary to elicit the observed systemic properties.
The input-output dose responses show that the output strengths of these sensors are different, i.e., some regulated promoters like PmerT and PluxI are strong while others like ParsR and PcusC are relatively weak.
Kinetic modelling of PDCs has shown that these systems can exhibit a variety of input-output (dose-response) behaviors including graded response, ultrasensitivity and bistability.
The same was true for MAP, HR, CVP, urine output, noradrenaline dose, FiO2, PaO2/FiO2, thrombocytes, bilirubin, CRP and VEGF (Table 2).
After assessing the model output, inoculant dose ratios of 1 1, 1 2 and 1 6 TetR/EryR were selected to test experimentally, because the model suggested an identifiable trend with these doses would be observed.
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