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However, coexpression with either FAM150A or FAM150B led to robust activation of ALK neurite outgrowth activity.
DOI: http://dx.doi.org/10.7554/eLife.09811.005 In order to initially test whether FAM150A or FAM150B could activate ALK we assayed neurite outgrowth activity in PC12 cells.
However, the active components in L. rhinocerotis that play the role in neurite outgrowth activity need further investigation.
The synergism of the various active entities in these mushroom extracts may be responsible for the neurite outgrowth activity and further experiments are warranted to isolate and identify the compounds.
These results indicate that AG73-G3- PPG 5 AG73-G3- PPG 5 AG73-G3- PPG 5rite outgrowth activery on PLA films.
The pre-purified fractions were then lyophilized, reconstituted in pure water and tested for neurite outgrowth activity.
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In this study, aiming to fabricate the dynamically alterable neural network in vitro, the chemically modified surface with the photo-reactive self-assembled monolayer was applied to navigate the neurite outgrowth activities of differentiated PC12 cell in the spatially and temporally controlled manner.
Midkine (MK) is a growth factor with neurotrophic and neurite outgrowth activities.
Curcumin, G. biloba and L. barbarum extracts were also tested to compare the neurite outgrowth activities with those of mushroom extracts.
Our data suggest that this outgrowth promoting activity of PTEN is independent of mTOR activity.
Snake NGF-induced neurite outgrowth (neurotropic activity) was measured in the past by using PC12 cell or dorsal root ganglion bioassays.
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