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Unsurprisingly, the discount rate associated with outcomes was identified as a significant factor for many scenarios, due to the upfront cost of prophylaxis followed by a prolonged health gain in the future.
Thirty four of 61 patients (56%) had receptor expression detected by scintigraphy; no clear relationship with clinical outcomes was identified.
An over-riding focus on the quantification of technical intervention and adverse or undesirable outcomes was identified.
However, in the large phase 3 MONET1 study of motesanib plus carboplatin/paclitaxel in patients with nonsquamous NSCLC, which prospectively assessed associations between change in PLGF and overall survival, no association between PLGF change and outcomes was identified [ 24].
The persistence of these outcomes was identified in the observational Epidemiology of Diabetes Interventions and Complications (EDIC) follow-up trial, in which all subjects from DCCT were treated with long-term, intensive insulin therapy.
A qualitative study by Patterson (1993) demonstrated that an unexpected shift in health situation or pregnancy outcomes was identified as a high risk condition by pregnant women, while the expected changes were considered as no risk [ 51].
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After screening, a total of 15 trials that reported outcomes were identified.
Thus, the sole requirement is that exploratory outcomes are identified transparently as exploratory (for a list of frequently asked questions see https://cos.io/rr/ faq).io/rr/ faq
From a series of simulations using this model, a series of practical outcomes were identified regarding the feasibility of the broadside seismic transmission method.
Once it adopted the six-step method, these outcomes were identified as "reducing employee turnover and increasing productivity and innovation". Metrics were developed to monitor these, and targets were set before moving on.
A range of maternal and delivery-related risk variables and clinically important outcomes were identified by expert opinion and selected and weighted with ordinal logistic regression analysis.
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