Exact(2)
There is little doubt that, in certain patients, achieving and maintaining high levels of cardiac output is associated with improved outcomes; the difficulty lies in identifying those patients.
This problem is compounded by concerns about the subjective nature of back pain outcomes, the difficulty in masking participants to study treatment, and the strong skepticism of some researchers that CAM treatments can be effective, even when results are impressive.
Similar(58)
Again, as McNeill said of the Protestant outcome: "The difficulty of establishing consensus on a biblical basis tended therefore to widen the areas of tolerance within Protestant states".20.20
Although no specific intervention is associated with better outcomes, given the difficulty in studying outcomes in this rare condition and the success of this therapy for other foreign bodies in the eye, this course of action is reasonable.
Given the difficult nature of studying alcohol intake's effect on human outcomes and the difficulty of separating the choice from the chooser, an effective study may need to make use of a policy experiment rather than just observe people's behaviour.
We initially considered having a more general outcome of "any haemorrhagic event" but decided against this given the disparate nature of the events, the rarity with which some occur, the lack of relevant ICD-10 codes for some outcomes, and the difficulty of applying definitions requiring clinical adjudication to routinely collected data.
In the Petro Ranger's case, what finally happened still baffles those involved, and yet the outcome exposes the difficulty of suppressing piracy in a globally gilded economy.
It was less than a quarter of their $325m total exactly two years ago, but still a respectable outcome given the difficulty of obtaining consignments.
Shibley Telhami of the Brookings Institution concludes that al-Qaeda is more likely to continue planning its attacks without regard to America's electoral timetable or outcome.Given the difficulty of thinking straight about the impact of any attack, or even whether there might be one, it is not surprising that reactions to the threat of "another 9/11" have been mixed.
The major reason for this poor outcome is the difficulty in the detection of early stage GC when treatment could improve long term survival of patients.
22 One of the disadvantages of this type of treatment is the perioperative pain, tenderness, blistering and sloughing of necrotic tissue, with possible hypopigmentation and scarring as the outcome and the difficulty associated with identifying recurrence in scar tissue.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com