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In secondary outcomes, significant differences in weight (p= 0.008), BMI (p= 0.001) and waist-to-hip ratio (p=0.020) were detected in the treatment versus placebo groups.
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Evaluating the clinical and radiological outcome, significant differences were only detected for range of motion and the Knee Score of the KSS.
The outcomes showed significant differences in the revisions carried out in all categories except Activities.
None of the secondary outcomes showed significant differences (table 1).
For Outcomes: Statistically significant differences between Zero Moves and One Move: Health Status, Received Income Assistance (p < 0.01).
None of the other outcomes showed significant differences between the two groups, apart from the percentage of knee injuries.
The results of the qualitative assessment support the results of the meta-analysis for outcomes with significant differences.
Results: For 112 participants with data available for analysis on the specified outcomes, no significant differences were shown.
We managed this issue by reporting differences in favour of CDSSs on at least one prescribing outcome and significant differences on the majority of prescribing outcomes.
For the insulin glargine arm of the study, we observed a statistically nonsignificant reduction in CIMT progression for the primary outcome and significant differences, favoring insulin glargine therapy for the secondary CIMT outcomes.
When comparing the data from the weather stations during the reference period with the modelled STAR outcome no significant differences are noticed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com