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In the previously published DREW primary outcomes paper we reported that the mean follow-up waist circumference was lower in all exercise groups compared to the control group and there was no difference in mean follow-up weight across groups.
The full methodology for HART-D has been previously described in the main outcomes paper (6).
A secondary outcomes paper from this study further explores the possible mediating effect of ESA on depressive symptoms [ 52].
In a recent health outcomes paper, Edelsberg and colleagues demonstrated worse outcomes and increased resource utilization in cSSSI patients who were prior antibiotic failures [ 19].
As discussed in the mental health outcomes paper [ 14] participating GPs may have felt the need to manage mental health symptoms when they first present rather than wait for further data as the general rate of return to follow up review appointments can be unpredictable [ 9, 34].
Finally, there was no significant effect of the mobiletype program on pathways to care, rather as reported in the mental health outcomes paper [ 14] it appeared that GPs conducted a mental health intervention at pre-test, implementing on average two pathways to care for most participants.
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As of December 2009, the primary outcome paper had been published for 16 of the multisite randomized clinical trials conducted in the CTN, testing various treatments for drug abuse, HIV risk behavior, or related problems.
A full description of all outcome measures are reported in the main RCT outcome paper [ 15].
The main outcome paper for this trial is currently in preparation.
We have published a main outcome paper that provides additional details about the R4R intervention [ 4].
More detailed description of ADAPT treatment is provided in the primary clinical outcome paper [ 27].
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CEO of Professional Science Editing for Scientists @ prosciediting.com