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Using diagnostic codes or clinical measurement values has little impact on the outcomes of proportion-based PQI when both numerator and denominator are equally affected.
The secondary outcomes of proportions of patients with toxicities and SAEs such as unexplained death and significant bleeding during the first six months will be compared using a chi-squared test.
Nevertheless, neither the primary outcome of proportion of patients with a greater than 50% reduction in headache frequency nor the secondary outcome of reduced mean headache days in a 28-day period showed topiramate as more efficacious than placebo in our meta-analysis of four RCTs.
The sample size of 1002 children and their parents total at baseline was determined by power calculations using the primary outcome of proportion of subjects with emergency department (ED) visits in the last twelve months taking into account a 25% attrition rate over 24 months leaving 801 total subjects at the end of the study.
The secondary outcome of proportions of patients with SAEs will be compared using a chi-squared test.
For all outcomes of interest, proportions are reported for both men and women at baseline and endline.
The objective of this study was to assess the clarity of outcome reporting, proportion of registered trials, and adequacy of outcome registration in RCTs published in top behavioral health journals.
These models have gained popularity in analyses of count outcomes with high proportion of zeros, but their selection and applicability can be data-specific [ 37, 38].
However, beyond samples of patients who are traced for research purposes, the actual outcomes of a substantial proportion of patients remain unreported and unknown.
Ascertainment of contact information is a prerequisite for tracing, which can reveal outcomes of a large proportion of patients LTFU.
So in watching Iran's nuclear project, even a slight intelligence gaffe could have an outcome of historic proportions.
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