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Because more active nutritional support is essential to achieve complete nutrition and thereby improve patient tolerance and outcomes, modified PPN solutions have been tried and successfully applied [ 17].
To detect factors associated with poor functional outcomes (modified Rankin scale [mRS] ≥5) at discharge and 3 month, we used univariate and multivariate regression analyses.
Several successful programs in the United States, such as Access to Baby and Child Dentistry (ABCD) [ 35] and Head Start [ 27], constitute strong bases leading to better oral health outcomes; modified versions of these programs could be expanded to serve adults as well.
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It is unknown whether it is common for quality of life and health survey results to reach different conclusions from those of the primary efficacy outcomes, whether there is selective reporting of outcomes, or whether discordant results in these outcomes modify the conclusions of these trials.
Episodes of crisis were associated with poor outcome (modified Rankin Score 5 or 6, P < 0.05).
Functional outcomes were dichotomised into good outcome (modified Rankin Scale (mRS) 0 2) and bad outcome (mRS 3 6).
The primary outcomes included favorable outcome (modified Rankin scale [mRS] 0 2) at discharge and intracerebral hemorrhage (ICH) after tPA administration.
The primary endpoint was the dichotomised modified Rankin score at discharge: "favourable outcome" (modified Rankin score 0 or 1) or "unfavourable outcome" (score 2-6).
Treated and untreated groups both had very poor outcomes (3-month modified Rankin Scale 5 6 90% untreated versus 88% treated, death rate 71% untreated versus 67% treated), with no patients reaching a good 3-month functional outcome (modified Rankin Scale <2).
Brain metabolic distress and increased IL-6 levels were associated with poor functional outcome (modified Rankin Scale of more than 3, P ≤0.01).
Knoflach et al. [ 28] found age to be a significant inverse predictor of good outcome (modified Rankin Scale score) after ischemic stroke, but no hemorrhagic stroke patients were enrolled.
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