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The self-care outcomes model was developed based on the Outcomes Model for Health Care Research and literature review.
25 A BENESCO (Benefits of Smoking Cessation on Outcomes) model was used to simulate the consequences of tobacco use and the benefits of quitting (including medication costs and decrease in morbidity and mortality).
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The UKPDS outcomes model is based on the UKPDS, the longest follow-up study of patients with type 2 diabetes.
The UKPDS outcomes model is one of the more accepted simulation models, because it is based on prospectively registered data [ 13].
Each outcome model was rerun using only the subset of patients who received appropriate therapy.
The mortality outcome model was estimated by logistic regression.
The Context + Mechanism = Outcome Model was used to study the relationship between context factors, mechanisms and outcomes.
This single outcome model was primarily conceptualised as a model for cost data and the term cost is therefore used as short-hand.
Due to concerns that this variable might be problematic by artificially eating up variation in the outcomes, models were also run with this variable omitted.
For both outcomes, models were independently fit on 4 data sets, each of which contained one of the imputed household income values.
Similarly, the weights correct the RA estimator if the treatment model is correct but the outcome model is wrongly specified.
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