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Considering that these two ingredients may work independently as well as inter-dependently, the three treatment arms allow an investigation not only to determine the effectiveness of the combined psychoeducation and peer-support treatment condition, but also of how each ingredient impacts independently on particular participants' outcomes, minimising any contamination [ 26, 27].
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Our use of nationwide registries with virtually complete coverage and continuously updated data on demographic characteristics, hospital contacts and cancer outcomes minimised selection bias.
The main outcome measure was machine derived, and research nurses blinded to allocation undertook the assessment of other outcomes, thereby minimising the risk of bias.
Future improvements in cancer outcomes while minimising patient exposure to ineffective therapy will require a shift in oncology culture toward tumour profiling at diagnosis, with treatments based on molecular signature.
As with other patient-reported outcome measures, minimising respondent burden is important for the response rate and quality of the collected data [ 27, 28].
This non-linear, continuous age variable model shows that the poor child health outcomes are minimised at age 29 for the infant mortality outcome.
A pyramidal model of how primary health service organisations implemented the policy was constructed prior to knowing trial outcomes to minimise bias.
Therefore, blinded research nurses assessed outcomes to minimise detection bias.
The colposcopist was blinded to the woman's initial cytology status, her randomisation(s), and any clinical outcomes to minimise potential bias in assessment of the transformation zone.
Identification of risk factors for MDR organisms in patients presenting from the community with sepsis is necessary to help optimise patient outcomes and minimise the use of broad-spectrum antibiotics.
Maximising quality of life is an important treatment outcome to minimise morbidity and mortality rates in the management of CKD patients.
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CEO of Professional Science Editing for Scientists @ prosciediting.com