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The main objective of this study was to look for discrepancies between primary outcomes listed in protocols and in the subsequent completed reviews published on the Cochrane Library.
A downgrade also occurred if the protocol specified primary outcome(s) but the same outcomes listed in the review had no order of importance.
The effect of income grouping on birth outcomes listed on the birth records was estimated using odds ratios and Fisher's exact tests.
An upgrade also occurred if the review specified primary outcome(s) but the same outcomes listed in the protocol were not listed with any order of importance, i.e. primary or secondary.
The Cochrane Handbook recommends that up to a maximum of seven desirable and undesirable outcomes (listed in order of importance) that are essential for decision-making should be decided by reviewers during protocol development and included in the 'Summary of findings' section of the review.
The outcome (dependent) variables were the course outcomes listed above.
Age was a significant predictor of all CogState outcomes listed below.
Data on the primary and secondary outcomes listed below will be recorded.
This should be sufficient to calculate sufficiently precise estimates of the feasibility outcomes listed above.
For hospitalisations (HES database), outcomes listed as the primary discharge diagnosis were studied.
For most diseases such instruments are lacking for all types of outcomes listed above.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com