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It comprises 15 items that assess study purpose, design, sample, outcomes, interventions, results and clinical implications.
Pre-conditions, long-term outcomes, interventions, assumptions and indicators were displayed on the ToC map.
Owing to the heterogeneity of study outcomes, interventions and methods, a descriptive analysis was chosen over a meta-analysis.
Table 1 shows the main characteristics of the studies and participants; table 2 shows the outcomes, interventions, and quality assessments.
We used a search strategy which combined MeSH terms/keyword and text search terms relating to the outcomes, interventions and populations of interest (See additional file 1).
Descriptive statistics is performed for the secondary outcomes (interventions registered, adherence, patient's attitude towards medicines, satisfaction with medication information and satisfaction of the general practitioner and community pharmacist).
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Management-level implementation outcomes (intervention cost, feasibility, and sustainability) were assessed at study conclusion in a qualitative interview with OTP management.
Although hyperglycemia is associated with adverse patient outcomes, intervention to normalize glycemia has yielded inconsistent results.
Information regarding primary and secondary outcomes, intervention, study sponsors, and sample size were extracted from registrations and publications.
The UK Medical Research Council guidance for developing and evaluating complex interventions recommends conducting a process evaluation to provide insight into unexpected outcomes, intervention fidelity and factors influencing implementation [ 18].
Application, population, comparator, outcome, intervention.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com