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Although our study was not designed to investigate whether migraine patients with UAs respond better to triptans than those without, it offers meaningful evidence-based data on outcomes for comparison.
Analysis for the primary outcome will use logistic regression of paired binary outcomes for comparison of diagnostic accuracy measures of MRE and USS within patients, allowing adjustment for clustering by centre.
Details of the three most recent cesarean deliveries reported in medical records and operating theater logbooks as taking place between 12 and 60 hours before arrival of the data collectors were documented using a structured checklist designed to collect case information and outcomes for comparison with observed deliveries.
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However, we also examined total mortality as an outcome for comparison with previous findings.
Therefore, a significant outcome of Comparison 2 often implies a significant outcome for Comparison 3, provided that the classifier has a high specificity (Table 1).
The primary outcome for comparison between the networks will be a composite indicator of mortality or any of the four major neonatal morbidities (severe neurological injury, severe ROP, NEC, and BPD).
Our relative small sample size limited the number of outcomes available for comparison.
No trial contributing to the primary outcomes for this comparison was judged to be of high risk of bias.
Primary outcomes for the comparison of BT versus MAC are presented elsewhere [ 11] but indicated a clear advantage for BT over MAC following acute treatment.
We were unable to conduct meta-analysis, given the substantial heterogeneity in the type of CCDSSs and the outcomes evaluated, however we calculated the effect sizes of the primary outcomes for easier comparison of the study effects.
In 30 reviews, no meta-analysis was performed for primary outcomes in 65 comparisons: for 9 comparisons, no RCT existed for the primary outcomes; for 53 comparisons, only 1 RCT existed for the primary outcomes; and for 3 comparisons (2, 3, and 3 RCTs), no meta-analysis was performed for the primary outcomes.
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