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Firstly, the 33 outcomes' baseline assessments were compared via paired t test (since Kolmogorov Smirnov testing confirmed normality) for any group baseline difference.
The outcomes' baseline values (measures before treatment) were entered as a covariate to adjust for baseline differences between treatments.
Data on chemotherapy, treatment outcomes, baseline characteristics with routine blood chemistries, and follow-up were fully available for the 161 assessed patients.
Untargeted metabolomics analysis revealed that SN significantly altered 33 (160 mg/day) to 45 (80 mg/day) different metabolites, 13 of which were related to changes in functional outcomes; baseline concentrations of 99 different metabolites predicted functional improvements with SN.
We used analysis of covariance for a factorial study for the main continuous outcomes, baseline symptom severity, and potential confounders as appropriate (in this case smoking was included in the models as it is related to symptom severity).
In addition to clinical and behavioral outcomes, baseline data are collected to describe the characteristics of study participants (providers and patients) and compare these characteristics between intervention groups assigned by randomization.
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Secondary outcome baseline scores were similar between groups (Table 3).
4. Outcome: baseline and follow up mean scores (and baseline standard deviation (SD)) for pain intensity.
We will use: Statistical Model #1: Outcome (after 17 weeks) = outcome (baseline) + study group + covariates.
Primary outcome: baseline and 1-year follow-up telephone survey response rates.
However, in predicting catastrophic outcome, baseline serum glucose remained in the model overcoming the impact of diabetes (24).
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