Exact(4)
We sought to examine both the overall effect of CYP19A1 and to explicitly test for gene*sex interactions and sex-specific differences in these genetic variants and outcome using two independent coronary artery disease (CAD) populations, one with acute coronary syndromes (ACS) and one with stable CAD.
Testing the primary outcome using two sided t-testing will require at least 224 dyads (patients and caregivers) to complete the study (112 per arm).
This study intends to evaluate the capacity of SAPS 3 on predicting ICU patient outcome, using two of its equations – global and Central/South American – and to compare it with the APACHE II score in a general ICU in Brazil.
Two logistic models were considered for a dichotomized cprs outcome using two cut-off values of cprs>25 and cprs>40 to produce two binary outcomes with prevalence 26.5% and 8.6%.
Similar(4)
Meta-analyses were then used to calculate overall summary estimates of effect for the association of childhood SEP with each physical capability outcome using one childhood SEP estimate for each study and including all studies regardless of the indicator of SEP they had used.
We pre-specified that we would assess the impact of any non-compliance on the primary outcome using three definitions.
Table 2 presents the estimated short-term effects for each cohort and mortality outcome, using three averaging periods of exposure, and either using or not using the individual spatial weights.
29 We made 21 comparisons between exposure and outcome using five different models, and it is possible that some statistically significant findings occurred owing to the occurrence of false positive associations expected with multiple comparisons.
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