The three outcomes ranked of least importance were: duration of hospitalization, death after a prolonged illness, and occurrence of delirium.
The list of outcomes ranked as critically important to weight management in pregnancy is provided in appendix 1 on bmj.com.
Tables 4 and 5 summarise the findings and quality assessment (GRADE) for outcomes ranked as critical for decision making.
Of the 11 potential outcomes, the three outcomes ranked of highest importance were: permanent brain dysfunction, quality of life, and requirement for long-term institutional care.
11 Given the potential importance of weight management interventions in pregnancy, we systematically reviewed the effects of dietary and lifestyle interventions on various outcomes ranked for their importance.
Relapse frequency and its surrogates, MRI T2 or gadolinium-enhancing lesions, still represent the most common outcome measures for evaluating treatment efficacy, notwithstanding that relapses came last among 12 clinical trial outcomes ranked for credibility two decades ago by a large group of multiple sclerosis clinical trialists (Noseworthy et al., 1989).
The three round decision Delphi process has proven to be effective for developing outcomes, ranking key priorities in primary care eHealth development, and achieving consensus among the most influential experts in that field.
Results: Correlation of VPM K1 values in ipsilateral TL with surgery outcome rank in individual patients was highly positive (Pearson r = 0.7573, p = 0.0017, n = 14).
These results indicate that Osteopontin rank is a good predictor of survival outcome rank within a study.
Since GSE14333 contained DFS follow-up, the Kaplan Meier survival curves were plotted again as predicted by the outcome signature and reproduced the outcome ranking (i.e. best to worst survival time) for all five subtypes.
