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For the prevalent syphilis outcome, prevalence ratios will be calculated to avoid overestimation of measures of association which would result from logistic regression [ 23].
The resulting impact of the methodology on health outcome prevalence estimation was assessed.
We carried out a sample size calculation for the primary outcome, prevalence of HIV testing.
For each outcome, prevalence was estimated in relation to annual household income (6 categories).
Poisson regression with scale parameter adjusted by χ2 showed variable performance depending on the outcome prevalence.
Additionally, outcome prevalence rates did not differ significantly (p ≥ 0.36) by study cycle (not shown).
Similar(21)
Main outcome result: Prevalence rates of mental disorders most commonly seen in primary care practice (mood, anxiety, somatoform, eating and alcohol disorders).
In order to compare observed concentration indices when outcome prevalences differ, the concentration index can be normalised by dividing by 1 minus the prevalence (Wagstaff, 2005).
In order to compare observed concentration indices when outcome prevalences differ, Wagstaff (2005) suggested normalizing the concentration index by dividing by 1 minus the prevalence.
Although we modelled treatment costs, these were not influential in the cost-consequence analysis due to these very small differences between outcome prevalences and are not shown here for simplicity.
Much higher treatment costs for PPROM patients meant that the small differences in outcome prevalences between the standard and Vision ALD arms of the model were more significant in this model.
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