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While there are always companies that have such spectacular outcome potential for which it's worth breaking the rules, this should be the exception and is not a sound basis for a fund strategy in today's context.
To determine the pregnancy outcome potential of mosaic embryos, detected by means of preimplantation genetic screening (PGS) with the use of next-generation sequencing (NGS).
Given the small sample size and limited data on outcome, potential benefits of albumin solutions in ARDS patients remain uncertain.
For example, for the association between exposure during pregnancy and neonatal outcome, potential confounders include: maternal age, education, family income, gestational age, gestational weight gain, alcohol and tobacco.
Based on the lack of evidence documenting improved outcome, potential deleterious effects, and substantial economic strain on the health care system, we agree with the recent review by Alderson and colleagues [ 19].
We selected these topics based on the level of possible clinical impact, the level of controversy, known or suspected variation in practice, potential importance for scientific outcome, potential for development of evidence-based medicine recommendations, and availability of evidence.
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However, HITH interventions may have different components and varied outcome potentials in different health care systems.
Limitations include a lack of formally adjudicated outcomes, potential information bias, and missing data.
Data included all asthma related outcomes, potential covariates, characteristics of the study, design, population, intervention/exposure, comparators, and co interventions.
Data concerning participants, interventions, outcomes, potential effect modifiers and trial quality characteristics were extracted independently in duplicate.
A detailed description of measurement of study outcomes, potential confounders and mediators is given in the electronic supplementary material (ESM) Methods.
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