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Agreement of identification (AI) between MALDI and classical methods (API®, PHOENIX®) was defined as the identical outcome of identification of a given isolate by all three methods.
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The initial aim was to understand how various types of end users undertook the task of identifying individuals, including the data used, the initial evidence that was usually available, the desired outcome of the identification, and the amount of uncertainty that could be tolerated.
The outcome of the identification by MALDI-TOF MS was compared to that obtained by 16S sequencing, which for the purpose of this work was considered the gold standard, and other methods (API®, PHOENIX®) currently used in our laboratory.
Fig. 2 Sample outcome of FSA tag identification frames (N=4 and L=4).
The outcome of this putative identification was further validated by the fragmentation pattern of the respective standards of the same set of metabolites (Additional file 3).
Traumatic brain injury patient-reported outcome measure: identification of health-related quality-of-life issues relevant to individuals with traumatic brain injury.
The primary outcome was identification of a diagnosis of COPD according to the predefined eight algorithms.
The silent course of PC and its explosive fatal outcome have hindered studies of identification of early biochemical and genetic alterations that could help us diagnose the disease at a curable stage and develop successful therapeutic strategies.
In addition to assessing clinical outcome, the identification of risk factors and the pathologic confirmation of anterior horn cell involvement in patients with WNV-associated acute flaccid paralysis remain important public health goals.
In colorectal cancer, CD3, CD4, CD8, CD20, Granzyme B, and FoxP3+ tumor infiltrating lymphocytes (TILs) have been identified as potential indicators of outcome, while the identification of cytotoxic T-lymphocytes, mast cells and dendritic cells as elicitors of anti-tumor responses has underlined new avenues for potential immunotherapies [3], [4], [5].
Main Outcome Measure: Identification of perceptual-motor elements that underlie skilled stair descent and that are directly quantified from standard video recording.
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