Sentence examples for outcome mouse from inspiring English sources

Topics included drug design, target identification, early detection, cancer stem cells, microRNAs, genome wide approaches to determining risk and outcome, mouse models, and tumor microenvironment.

In order to more specifically investigate the relationship between HO-1 and ICH outcome, mice expressing human HO-1 driven by the glial fibrillary acidic protein (GFAP) promoter (GFAP·HMOX1 mice) were tested in a model of in situ parenchymal hemorrhage.

Following a similar strategy, we investigated the effects of osmolytes such as trehalose, proline, and sucrose as additives to the traditional cryoprotectant dimethyl sulfoxide (Me2SO) in modulating the cryopreservation outcome of mouse neuroblastoma (Neuro-2a) cells.

We have previously shown that in vitro interactions between human PMN and C. gattii can be used for a complimentary evaluation of virulence outcome in mouse models, and to assess the likely outcome of initial interactions between C. gattii and phagocyte cells [10], [29], [31].

By inhibiting PHD1 in CRC cells carrying wild-type or DNA contact mutant p53, we show increased cell death in response to chemotherapy and improved disease outcome in mouse models of CRC.

From the values of the parameters at different time points shown in Fig. 1E, F, G, H, group mean values were determined (Fig. 1I) and an overall recovery index for each animal was calculated (Fig. 1J) indicating an improved outcome in mice grafted with L1 overexpressing SENAs when compared to mice grafted with wild-type SENAs or sham-injected with PBS.

Indeed, the literature includes numerous examples of drugs that improved outcomes in mouse models but did not have a similar effect in humans.

Survival of wt mice was also significantly prolonged by TNF484 treatment (p < 0.05), which indicates a better outcome in mice receiving anti-inflammatory therapy.

Mice treated with PPMO before and after VEEV infection were completely protected from lethal outcome while mice receiving only post-infection PPMO treatment were partially protected.

Here, we evaluated whether targeted delivery of MSCs with triple PSGL1/SLeX/IL-10 engimproves improves therapeutic outcomes in mouse experimental autoimmune encephalomyelitis (EAE), a murine model for human MS. We found PSGL-1/SLeX mRNA transfection significantly enhanced MSC homing to the inflamed spinal cord.

Here we investigated whether the lectin pathway contributes to stroke outcome in mice and humans.