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We name the outcome method by stochastic-based large margin one-class support vector machine (SGD-LMSVC).
Table 1 Characteristics of mechanical studies Study n Outcome Method Conclusion Klitzman et al. [17] 8 fresh frozen human ankles Syndesmotic gap Tibiofibular movement Laxity due to cycling Cycling at submaximal loads in six-degrees-of-freedom-machine Dorsal/plantar flexion; internal/external rotation and inversion/eversion Good alternative for syndesmotic fixation.
The proxy outcome method is a general approach which provides estimates and adjustments for effects of unmeasured confounders.
In the current study, the proxy outcome method was adopted to control the effects of unknown confounders.
We then applied the proxy outcome method as the only means of adjusting for potential confounding effects.
The papers by Tchetgen Tchetgen and Liang et al. provided detailed discussion on the methodological framework of the proxy outcome method [ 17, 19].
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However, the outcome methods for the groups were the same.
Outcome: methods for follow-up of the outcome of examinations short and longer term.
Outcome methods have also varied.
Using multiple outcome methods, such as blind clinician raters, would strengthen future research.
Furthermore, to fully exploit the therapeutic potential of MSCs in clinical trials and correlate molecular characteristics to clinical outcome, methods for more stringent characterization are crucial.
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