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Background: In acute ischemic stroke, magnetic resonance diffusion-weighted imaging (DWI) is increasingly used to select patients for inclusion or as a surrogate outcome marker in clinical trials, or in routine practice.
The aim of this study was (1) to determine the longitudinal progression of FVCpp in patients with MDC1A, analyzing both ambulatory and non-ambulatory cohorts as well as those on or not on ventilation support (VS) and (2) to determine if FCVpp is a viable outcome marker for progression of disease.
The threshold of 6.6 ng/ml in serum LEP levels is confirmed as an outcome marker.
Improvement in the outcome marker, healthcare-associated Staphylococcus aureus bacteraemia, has not clearly been shown.
However, it does not incorporate the exacerbation of COPD, which is an important outcome marker.
The strongest evidence we found for an outcome marker was tumor TP53 mutation.
Similar(38)
Despite numerous trials showing that written sedation algorithms beneficially affect important outcome markers of oversedation, including mechanical ventilation duration [2, 11 13], only 55% of the responding intensivists have a written sedation procedure in their ICU.
It is important to investigate outcome markers relevant to patients.
There is great need of disease assessment and outcome markers in pSS.
Early mechanistic endpoints, which can serve as intermediate outcome markers in TBI trials, are still lacking.
Patients' clinical outcome markers were recorded prospectively during rounds and entered into a database.
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