Nevertheless, we reached sufficient statistical power for the primary outcome, limitations in activities.
We cannot exclude that we selected highly motivated and compliant patients with fewer outcome limitations.
This included systematic assessments of all randomised controlled trials across five main domains for each outcome: limitations of the study design and execution; inconsistency, indirectness, and imprecision of results; and publication bias.
Measurement at 12 weeks after delivery showed a consistent difference in favor of the experimental intervention but only the primary outcome limitations in activities measured with the RDQ reached statistical significance (Table 3).
Our findings differ from other studies that show a significant association between post-stroke depression and functional outcome limitation and between depression and functional outcome in patients with other medical problems [ 9, 15, 53].
"Main findings" may sound rather limited, but actually includes everything from trial design and eligibility criteria to the outcomes, limitations, and interpretation of a study.
This article reviews the development of colorectal stents, designs, materials, various types of colonic stents used in the treatment of colonic strictures, indications for their insertion, outcomes, limitations, complications, and future directions of the colonic stents.
Despite the strong study design to assess the efficacy of the HCP delivered intervention on outcomes, limitations and potential problems have been considered.
In contrast, in unadjusted analyses from a small study of 19 children, Inal et al. (2007) found no significant associations between total indoor molds or four specific genera including Penicillium, and symptom or lung function outcomes; limitations of this study reduce its importance.
Therefore, characteristics of an ideal agent for the treatment of multiple sclerosis would include oral administration (for convenience), clinically significant effects on disease- and patient-oriented outcomes, limitation of the disease process and reduced disability, and good tolerability.
Continued follow-up of the established high-quality occupational cohorts would be worthwhile, although the scientific yield may be limited because exposure and health outcome misclassification limitations can probably not be remedied.
