Although both labour dystocia [ 4, 7] and domestic violence during pregnancy [ 1, 2] are associated with adverse maternal and fetal outcome, evidence in support of a possible association between experiences of violence and labour dystocia is sparse.
Although both labour dystocia and domestic violence during pregnancy are associated with adverse maternal and fetal outcome, evidence in support of a possible association between experiences of domestic violence and labour dystocia is sparse.
The FDA's draft guidance on the use of patient-reported outcome measures in support of labeling claims [ 32] encouraged developers and researchers to identify a MID or MCID as a benchmark for interpreting the clinical importance or relevance of study results to patients – though the more recent definitive guidance has omitted this recommendation [ 33].
To discuss issues in the design of a measurement strategy related to the use of patient-reported outcomes (PROs) in support of a labelling claim.
Demand for economic and outcomes data in support of drug formulary listing in private and government-sponsored health programs has led to fundamental changes in drug development.
Although many of the drugs listed in Table 1 were associated with smaller improvements in patient outcome, the data in support of adjuvant chemotherapy for NSCLC were even more impressive than those for trastuzumab.
Use of single-agent trastuzumab in patients not suitable for chemotherapy might be an option, although limited outcome data are available in support of this approach.
Among the general GBM population, no randomized trials have defined the optimal extent of resection, though on first principles most agree that the more that can be safely removed, the better the apparent outcome, with retrospective data in support of this approach.
Furthermore, students also significantly increased their understanding of structural engineering, particularly with respect to the need to reinforce joints by tying them together to reduce load, an outcome in direct support of the second objective of the module.
Discussion summaries were presented in plenary sessions in support of outcomes for widely enhancing the science and policy of DRR.
