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In this protocol the outcome hierarchy and plans for analyses were presented.
In this protocol the outcome hierarchy and analyses plans were presented and these are published in this present publication.
Proper adjustments according to problems with multiplicity (see below) should be estimated based on the outcome hierarchy specified in the protocol.
The outcome hierarchy and a specific, detailed description of every other relevant aspect of the trial methodology should be described in a protocol, which should be registered (e.g., at http://www.clinicaltrials.gov) and published in a journal preferably before randomisation begins [ 17, 40, 46].
Problems with multiplicity has major implications for the interpretation of the confidence interval and the P-value and this is one reason why it should be mandatory to report a predefined outcome hierarchy including a clear definition of a primary outcome before conducting a randomised clinical trial [ 17, 40, 46].
Similar(55)
The outcomes theory background to VMEP outlines the concept of outcome hierarchies: "a cascading set of causes in the real world" (Duignan 2012a, p. 1).
Further, future research is warranted in examining more specifically how Porter's outcome measures hierarchy framework fits within the context of SCI and SHCs.
The outcome depends on hierarchy level, which highlights the utility of considering phenological sequences within a hierarchical framework.
A15 Cardinal Affirms Zero Tolerance Cardinal Anthony J. Bevilacqua of Philadelphia, saying the outcome of the hierarchy's Vatican meetings had been misunderstood, said all American cardinals were firmly agreed on a zero-tolerance policy toward any Roman Catholic priest considered guilty of sexually abusing minors.
This model explains the ranks as the observable outcome of a hierarchy of underlying normal performances of horses in competition.
Emphasizing this outcome enabled the hierarchy of the IHD to maintain the concept of eradication, which prevailed in 1955 in the Eighth World Health Assembly, and they voted to adopt DDT as a primary tool in the fight against malaria (35 ).
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CEO of Professional Science Editing for Scientists @ prosciediting.com