The molecular response remained consistent over time regardless of MRI outcome, excluding the possibility that attenuated IRG regulation explained the variable response to IFNβ.
We did an additional analysis using stroke as an outcome, excluding transient ischaemic attacks.
A secondary, per protocol analysis will be performed for the primary outcome, excluding patients with major protocol violations.
We conducted sensitivity analyses on unlogged data for all continuous outcomes and on logged data for the primary outcome excluding trials with high risk of bias.
In this study, we have found no priority of RC, RC + CRP and CRP alone in predicting AP outcome, excluding GBS disease and necrotizing cases.
Studies were included if human cases of infectious diseases were the outcome, excluding animal, vector, or vaccine studies in order to restrict the scope of the review.
However, the confidence interval for the primary outcome excludes a treatment effect of 10 points, which we designed the trial to detect.
Therefore, after obtaining funding which enabled us to increase our sample size to the current sample size of 680, we decided to study a composite adverse maternal outcome excluding progression to severe disease.
The comparison between the more extreme (categorical) VL outcomes excluded 335 patients (42.7%) with intermediate VL in order to reduce the potential misclassification (overlapping) between patient groups [26], [43].
Analyses of secondary outcomes excluded cases with missing outcome information (the primary outcome, return of spontaneous circulation, was ascertained in all study subjects).
