Two authors (AR, AS) then went through each extracted learning outcome, double-checked its relevance to EBHC as per the pre-specified competency list, and made the final decision regarding the choice of coding, i.e. the EBHC competency that it addressed.
However, they failed to show a significant association between hypomagnesemia and hard renal outcome (doubling of SCr and initiation of renal replacement therapy [RRT]), probably due to low statistical power (14).
Then we assessed whether the pair-wise combination of the tests could lead to a better evaluation of active tuberculosis diagnosis and we calculated the probabilities for the potential outcomes (double positive, double negative and discordant results) given the disease status.
In order to assess inter-rater reliability, a second coder who was naive to predicted outcomes double-coded a 20% section of the data.
In this study, we demonstrated that high plasma copeptin concentration was strongly associated with the risk of severe renal outcomes (doubling of plasma creatinine concentration and/or ESRD) in patients with type 2 diabetes and albuminuria.
Positive staining was scored by two independent investigators without the knowledge of patient outcomes (double-blinded) according to the staining area and intensity as described by (Bachmann et al, 2008).
The proportion of cases with excellent two-year clinical outcomes doubled, but 47% of cases remained in need of continuing treatment for their persisting symptoms and/or disability, or risk of recurrence.
A previous study showed that the persistence of glomerular and extraglomerular macrophagic infiltrates after therapy correlates with long-term renal-function outcomes (doubling of serum creatinine and end-stage renal disease) [ 32].
The US National Institute of Mental Health (NIMH) Multimodal Treatment study of ADHD (MTA) showed that careful medication management can significantly improve outcomes, doubling the normalisation rate from 25% in routine community care to almost 60% when using a strategy of careful dose titration and frequent monitoring of outcome.
China has the ultimate option to ignore any unfavorable outcome, and double down on its ongoing efforts to consolidate its claims across the South China Sea.
