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To put it mildly, therefore, the chances for a negotiated outcome do not look good.Might they improve?
The rates of outcome do not differ from the distribution published by Coudeville et al. [25].
However, as the mutation described here affects an acceptor-splice site and leads to skipping of the upstream exon in the two-exon-skip outcome, these findings illustrate that the exons involved in the two-exon-skip splicing outcome do not solely depend on whether the mutation affects an acceptor- or donor-splice site.
Owing to biological heterogeneity, the histological diagnosis and expected clinical outcome do not match in a significant number of patients.
Conversely, exposure and outcome do not necessarily correlate, given the complexity of pathogenesis and masking by competing risk factors.
Studies evaluating PPC as outcome do not always specify the specific disease and the criteria used for diagnosis are not consistent [ 1].
Similar(45)
But the prospects for such a benign outcome don't seem good.
Being overly optimistic leads to disappointment when an expected positive outcome don't happen as anticipated.
Whatever the outcome, don't feel bad about it.
Pregnancy outcome did not change significantly with increasing amniocentesis experience.
Outcome does not differ from FCR-treated patients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com