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In the end, studies that can more robustly delineate the temporal sequence of exposure and outcome are required.
Pencina, for example, states that "very large 'independent' associations of the new marker with the outcome are required to result in a meaningfully larger AUC"[ 22].
Methodological guidance for the derivation of CDRs states that approximately 10 subjects with the primary outcome are required for every predictor included in the decision rule.
In general improved models of prediction of disease outcome are required to allow the clinician to design more appropriate treatment modalities for prostate cancer patients.
However, the sample sizes are small, and larger studies linking PTHrP expression to outcome are required to demonstrate any prognostic significance of this observation.
Further focused studies addressing the relationship of triage category with LOS and its impact on short and long term outcome are required.
Similar(53)
Private relations had taught her the opposite lesson - that only the shadow of a negative outcome was required to contradict any plan, any hope.
Finally, the outcome was required to be objectively confirmed AMI.
Nevertheless, if the purpose is to improve health, then a robustly measured health outcome is required.
In order to carry out a CEA, a well-defined treatment outcome is required.
Further investigation of factors associated with improved visual outcome is required.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com