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CMI authors and reviewers should consider these helpful proposals when designing, reporting and assessing intervention and outbreak studies.
There were 102 samples analyzed during the combined watershed and outbreak studies that were positive for EcO157.
This is ideal for contact tracing and outbreak studies, as epidemiologically related individuals are likely to share the same fingerprint.
The study included patients admitted to hospital, subjects of a seroepidemiologic cohort study, and participants identified from outbreak studies in Singapore.
These data will aid interpretation of future outbreak studies.
Data were available from thirty-three outbreaktbreak studies where multiple specimens were sequenced.
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Furthermore, although typing schemes based upon common variation are quite useful, it may often happen that rare variants are more informative for tracking the history of specific strains, as might be required in an epidemiological outbreak study.
This underestimate is reflected in the results of the outbreak study's serological survey.
At the beginning of the outbreak study, the culture results from different samples, including the irrigation fluids, were negative.
Phylogenetic analysis showed that similar to findings from the 2001 outbreak study (8 ), viruses from Bangladesh and India clustered and diverged from the viruses from Malaysia.
Other studies suggested that group 2 VACV might be associated with severe illness, but such is not the case in the outbreak studied; however, very limited information is available about the relation between viral genotype and virulence in humans.
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